Nicole Paulk

Nicole Paulk

Company: University of California, San Francisco

Job title: AAV Gene Therapy Prof


Dr. Nicole Paulk is an Assistant Professor of AAV Gene Therapy in the UCSF Department of Biochemistry & Biophysics in San Francisco. Dr. Paulk has a BS in Medical Microbiology, a PhD in AAV Gene Therapy and Regenerative Medicine from OHSU, and completed her Postdoctoral Fellowship and Instructorship in Human Gene Therapy at Stanford University prior to starting her lab at UCSF. She is a pioneer in the development of next-generation AAV platforms for gene repair, gene transfer and gene editing for numerous rare diseases and cancer, directed evolution to evolve novel viral capsids, and comparative multiomic approaches to interrogate translational AAV biology. Dr. Paulk is a global KOL in gene therapy and consults extensively for big pharma, writes guidance for the FDA, and sits on the SABs for Sarepta, Astellas, Dyno Tx, CEVEC, Excision Bio, Whitelab Genomics, GRO Bio, John’s Hopkins Gene Therapy Initiative, and a stealth newco. She is regularly quoted in STAT, Endpoints, Phacilitate, GEN, Biopharma Dive, Wall Street Journal, and is a regular guest on Biotech Clubhouse. Dr. Paulk sits on the Scientific Editorial Boards of the journals Nature Gene Therapy and Human Gene Therapy, and sits or Chairs numerous committees within the American Society of Gene & Cell Therapy. Dr. Paulk’s prior work has been spun out into two successful life science companies (LogicBio Therapeutics and Yecuris), and she has invented numerous AAV gene therapy technologies that have been shared/licensed to dozens of international gene therapy companies and nonprofits groups working in rare diseases. 

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