Adam Fowler

Adam Fowler

Company: LocanaBio

Job title: Senior Vice President & Head of Technical Operations, CMC


Adam Fowler joined LocanaBio in 2020 as Senior Vice President of Technical Operations and Head of CMC. Adam has a proven track record of successfully leading and supporting early-to-late stage CMC drug development activities with over 20 INDs and through the commercial approval process of 2 licensed biologic products (Ruconest® and Reblozyl®). Adam has extensive experience spanning a broad range of biologics process development, manufacturing and supply chain activities across multiple biologics modalities, including ~9 years in gene therapy, including roles in process development where he drove the development of and transfer of scalable processes for multiple viral vectors types (AAV, Lentivirus and Adenovirus), and later in a manufacturing capacity where he led internal manufacturing operations at Genzyme’s Gene Therapy Operations (GTO) manufacturing site in San Diego. Prior to Locanabio, Adam spent approximately 4 years at Celgene (and BMS after the acquisition) as Senior Director of Biopharmaceutical Development and Manufacturing, where he led the group responsible for all outsourced biologics DS development and manufacturing activities for the Celgene protein biologics portfolio, during which time he supported the US (2019) and EU (2020) approvals for Celgene’s first commercial biologic product Reblozyl®. Prior to Celgene/BMS, Adam was Vice President and Head of CMC at AnaptysBio, where he established their initial CMC group, and led all CMC activities to get their first 2 mAb products into the clinic, and previous to that, Adam led CMC for Salix Pharmaceuticals’ (Salix acquired San Diego-based Santarus in 2014) biologics programs, a tenure which included the BLA filing and 2014 FDA approval of Salix’s first biologic product RUCONEST®. Earlier in his career, Adam held development and manufacturing positions of increasing responsibility at NexBio (now Ansun Biopharma), Genzyme, Cell Genesys and Eligix.  Adam received his B.S. and M.S. degrees in Biotechnology from Worcester Polytechnic Institute.

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